Experimental assessment of immunobiological activity of the roncoleukine immunomodulatory agent

详细

We have found that roncoleukine (recombinant interleukin 2, rIL-2) when double administered in the dose of 5000 IU/kg of body weight or 10000 IU/kg of body weight enhanced functional activity of the effector cells of the delayed type hypersensitivity. It was demonstrated that the selective action of rIL-2 in the dose of 10000 IU/kg of body weight induced protective effect (more than 50%) in the mice experimentally infected with T. spiralis.