Email this article Experimental assessment of immunobiological activity of the roncoleukine immunomodulatory agent
- Authors: Mamykova O.I.1
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Affiliations:
- Skryabin All-Russia Research Institute of Fundamental and Applied Parasitology of Animals and Plants
- Issue: Vol 42, No 2 (2016)
- Pages: 184-187
- Section: Veterinary
- URL: https://bakhtiniada.ru/1068-3674/article/view/229514
- DOI: https://doi.org/10.3103/S1068367416020087
- ID: 229514
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Abstract
We have found that roncoleukine (recombinant interleukin 2, rIL-2) when double administered in the dose of 5000 IU/kg of body weight or 10000 IU/kg of body weight enhanced functional activity of the effector cells of the delayed type hypersensitivity. It was demonstrated that the selective action of rIL-2 in the dose of 10000 IU/kg of body weight induced protective effect (more than 50%) in the mice experimentally infected with T. spiralis.
About the authors
O. I. Mamykova
Skryabin All-Russia Research Institute of Fundamental and Applied Parasitology of Animals and Plants
Author for correspondence.
Email: olgamamykova@yandex.ru
Russian Federation, Moscow, 117218
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