Synthesis and antitubercular activity of first glucuronosyl phosphates and amidophosphates containing polymethylene chains


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详细

Novel phosphorylated glycolipids based on glucuronic acid have been synthesized and shown to inhibit M. Tuberculosis H37Rv in vitro at a minimum inhibitory concentration of 12.5 μg/mL.

作者简介

E. Izmest’ev

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

O. Andreeva

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

R. Sharipova

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

M. Kravchenko

Ural Research Institute of Phthisiopulmonology

Email: kataev@iopc.ru
俄罗斯联邦, ul. 22 Parts”ezda 50, Yekaterinburg, 620039

B. Garifullin

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

I. Strobykina

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

V. Kataev

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

编辑信件的主要联系方式.
Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

V. Mironov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
俄罗斯联邦, ul. Arbuzova 8, Kazan, Tatarstan, 420088

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