Synthesis and antitubercular activity of first glucuronosyl phosphates and amidophosphates containing polymethylene chains
- Authors: Izmest’ev E.S.1, Andreeva O.V.1, Sharipova R.R.1, Kravchenko M.A.2, Garifullin B.F.1, Strobykina I.Y.1, Kataev V.E.1, Mironov V.F.1
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Affiliations:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Ural Research Institute of Phthisiopulmonology
- Issue: Vol 53, No 1 (2017)
- Pages: 51-56
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/215609
- DOI: https://doi.org/10.1134/S1070428017010092
- ID: 215609
Cite item
Abstract
Novel phosphorylated glycolipids based on glucuronic acid have been synthesized and shown to inhibit M. Tuberculosis H37Rv in vitro at a minimum inhibitory concentration of 12.5 μg/mL.
About the authors
E. S. Izmest’ev
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
O. V. Andreeva
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
R. R. Sharipova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
M. A. Kravchenko
Ural Research Institute of Phthisiopulmonology
Email: kataev@iopc.ru
Russian Federation, ul. 22 Parts”ezda 50, Yekaterinburg, 620039
B. F. Garifullin
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
I. Yu. Strobykina
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
V. E. Kataev
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Author for correspondence.
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
V. F. Mironov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
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