Corrective Effect of Gentabiferon-S on Weaned Piglet Immune Status and Its Effectiveness in Prevention of Intestinal Infections

Abstract

The objective of the survey was to study the corrective effect of the Gentabiferon-S preparation on the immune status of the weaned piglets and its effectiveness in prevention of intestinal infections. A positive effect of the preparation on the morphological and immunological variables expressing the increased levels was ascertained. The red blood cell count, the relative lymphocyte count, the relative and absolute T–lymphocyte counts, the relative and absolute B-cell counts, the complement system activity, the lysozyme level, the neutrophil phagocytic activity, the number of phagocytes, the phagocytic index, the spontaneous and stimulated NBT test, the neutrophil activation reserve and index, and the amount of total immunoglobulins increased by 10.8, 16.5, 16.8 and 14.0%, 21.0 and 20.0%, 23.5, 66.8, 15.9, 38.2, 16.2, 11.0 and 21.7%, 13.3 and 17.1%, and 9.7%, respectively. A high (100%) effectiveness of the preparation in prevention of the intestinal infections is ensured by the presence of the antibiotic with broad-spectrum antimicrobial activity and the porcine recombinant alpha and gamma interferon.