Email this article Synthesis of N-aryl-2-methyl-4-oxo-3,4,5,6-tetrahydro-2H-2,6-methano-1,3,5-benzoxadiazocine-11-carboxamides
- Authors: Gein V.L.1, Zamaraeva T.M.1, Dmitriev M.V.2, Nasakin O.E.3
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Affiliations:
- Perm State Pharmaceutical Academy
- Perm State National Research University
- I.N. Ul’yanov Chuvash State University
- Issue: Vol 53, No 6 (2017)
- Pages: 869-872
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/216350
- DOI: https://doi.org/10.1134/S1070428017060094
- ID: 216350
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Abstract
N-Aryl-2-methyl-4-oxo-3,4,5,6-tetrahydro-2H-2,6-methano-1,3,5-benzoxadiazocine-11-carboxamides were synthesized by three-component reactions of N-aryl-3-oxobutanamides with salicylaldehyde and urea in ethanol in the presence of NaHSO4 as catalyst. The product structure was determined by IR and 1H NMR spectroscopy and X-ray analysis.
About the authors
V. L. Gein
Perm State Pharmaceutical Academy
Author for correspondence.
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
T. M. Zamaraeva
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
M. V. Dmitriev
Perm State National Research University
Email: geinvl48@mail.ru
Russian Federation, ul. Bukireva 15, Perm, 614990
O. E. Nasakin
I.N. Ul’yanov Chuvash State University
Email: geinvl48@mail.ru
Russian Federation, Moskovskii pr. 15, Cheboksary, 428015
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