Negative impact of Imunofan modulation on a result of specific therapy of helminthiases


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Abstract

In the model system mice–A. tetraptera, cancelation of the nematode activity of Nilverm, in case of combined application with Imunofan, was detected. It was ascertained that Imunofan in a dose of 0.025 mg/kg, in case of double introduction, does not possess protective and selective effect on immune reactions. Joint effect of the drugs is determined by the primary stimulation of humoral immune response, which is dependent on T-helpers.

About the authors

O. I. Mamykova

Skryabin All-Russia Research Institute of Fundamental and Applied Parasitology of Animals and Plants

Author for correspondence.
Email: olga.mamykova@yandex.ru
Russian Federation, Moscow, 117218

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