Laboratory control results of inactivated vaccine immunogenicity against rhinopneumonia and salmonella equine abortion

Abstract

Laboratory control of immunogenicity in linear and outbred white mice of the experimental sample of the inactivated vaccine against rhinopneumonia and salmonella equine abortion was carried out. The associated vaccine protects against experimental infection by rhinopneumonia virus 87.5% of the immunized animals and against the injection of the salmonella abortion pathogen 100% of the immunized animals. Sufficiently high immunogenicity of the inactivated vaccine against rhinopneumonia and salmonella abortion is due to antigenic activity that provides synthesis of specific antibodies in high titers and immunomodulatory agents that stimulate immunobiological reactivity of the organism.