Отправить статью по E-mail Effect of Nanosecond RF Pulses on Mitochondrial Membranes
- Авторы: Zharkova L.P.1,2, Romanchenko I.V.1, Bol’shakov M.A.1,2, Rostov V.V.1
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Учреждения:
- Institute of High-Current Electronics of the Siberian Branch of the Russian Academy of Sciences
- National Research Tomsk State University
- Выпуск: Том 60, № 8 (2017)
- Страницы: 1314-1318
- Раздел: Article
- URL: https://bakhtiniada.ru/1064-8887/article/view/238563
- DOI: https://doi.org/10.1007/s11182-017-1214-4
- ID: 238563
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Аннотация
Effect of nanosecond RF pulses on the state of isolated mitochondria and their membranes is investigated. Mitochondrial suspensions are exposed to periodic RF pulses with durations from 4 to 25 ns, frequencies from 0.6 to 1.0 GHz, amplitudes from 0.1 to 36 kV/cm, and pulse repetition frequencies 8–25 Hz. The integrity of the mitochondrial membranes is estimated from their resistance to electric current. The possibility of opening of protein pores with nonspecific permeability is determined from a change in the mitochondrial volume by registration of optical density of organelle suspension.
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L. Zharkova
Institute of High-Current Electronics of the Siberian Branch of the Russian Academy of Sciences; National Research Tomsk State University
Автор, ответственный за переписку.
Email: Zharkova_lubov@mail.ru
Россия, Tomsk; Tomsk
I. Romanchenko
Institute of High-Current Electronics of the Siberian Branch of the Russian Academy of Sciences
Email: Zharkova_lubov@mail.ru
Россия, Tomsk
M. Bol’shakov
Institute of High-Current Electronics of the Siberian Branch of the Russian Academy of Sciences; National Research Tomsk State University
Email: Zharkova_lubov@mail.ru
Россия, Tomsk; Tomsk
V. Rostov
Institute of High-Current Electronics of the Siberian Branch of the Russian Academy of Sciences
Email: Zharkova_lubov@mail.ru
Россия, Tomsk
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