Email this article Determination of Cotinine in Urine and Wastewaters by High Performance Liquid Chromatography Coupled with Tandem Mass-Spectrometric Detection
- Authors: Jang M.1, Pirogov A.V.1, Maksimova A.A.1, Dobrovolskiy V.I.2, Stakheev A.A.2, Abramova J.V.2, Priadka A.A.2, Jaricov A.P.3, Nosyrev A.E.4, Rozhanets V.V.3, Shpigun O.A.1
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Affiliations:
- Department of Chemistry
- All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
- Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
- National Research Center of Pharmacy, Sechenov First Moscow State Medical University
- Issue: Vol 73, No 6 (2018)
- Pages: 272-279
- Section: Article
- URL: https://bakhtiniada.ru/0027-1314/article/view/163792
- DOI: https://doi.org/10.3103/S0027131418060044
- ID: 163792
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Abstract
A technique of extracting cotinine in urine and wastewaters, followed by its quantitative determination, using high performance liquid chromatography combined with tandem mass-spectrometric detection is presented. The method is characterized by low detection limits and high levels of efficiency and sensitivity. The optimal conditions for the solid-phase extraction of cotinine from urine and wastewaters are found. This technique makes it possible to reliably estimate the content of cotinine in the urine of active and passive smokers and in wastewaters.
About the authors
M. Jang
Department of Chemistry
Author for correspondence.
Email: mongjoo0813@gmail.com
Russian Federation, Moscow, 119991
A. V. Pirogov
Department of Chemistry
Email: mongjoo0813@gmail.com
Russian Federation, Moscow, 119991
A. A. Maksimova
Department of Chemistry
Email: mongjoo0813@gmail.com
Russian Federation, Moscow, 119991
V. I. Dobrovolskiy
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
A. A. Stakheev
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
J. V. Abramova
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
A. A. Priadka
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
A. P. Jaricov
Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
A. E. Nosyrev
National Research Center of Pharmacy, Sechenov First Moscow State Medical University
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
V. V. Rozhanets
Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
Email: mongjoo0813@gmail.com
Russian Federation, Moscow
O. A. Shpigun
Department of Chemistry
Email: mongjoo0813@gmail.com
Russian Federation, Moscow, 119991
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