Determination of Cotinine in Urine and Wastewaters by High Performance Liquid Chromatography Coupled with Tandem Mass-Spectrometric Detection
- Авторы: Jang M.1, Pirogov A.V.1, Maksimova A.A.1, Dobrovolskiy V.I.2, Stakheev A.A.2, Abramova J.V.2, Priadka A.A.2, Jaricov A.P.3, Nosyrev A.E.4, Rozhanets V.V.3, Shpigun O.A.1
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Учреждения:
- Department of Chemistry
- All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
- Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
- National Research Center of Pharmacy, Sechenov First Moscow State Medical University
- Выпуск: Том 73, № 6 (2018)
- Страницы: 272-279
- Раздел: Article
- URL: https://bakhtiniada.ru/0027-1314/article/view/163792
- DOI: https://doi.org/10.3103/S0027131418060044
- ID: 163792
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Аннотация
A technique of extracting cotinine in urine and wastewaters, followed by its quantitative determination, using high performance liquid chromatography combined with tandem mass-spectrometric detection is presented. The method is characterized by low detection limits and high levels of efficiency and sensitivity. The optimal conditions for the solid-phase extraction of cotinine from urine and wastewaters are found. This technique makes it possible to reliably estimate the content of cotinine in the urine of active and passive smokers and in wastewaters.
Об авторах
M. Jang
Department of Chemistry
Автор, ответственный за переписку.
Email: mongjoo0813@gmail.com
Россия, Moscow, 119991
A. Pirogov
Department of Chemistry
Email: mongjoo0813@gmail.com
Россия, Moscow, 119991
A. Maksimova
Department of Chemistry
Email: mongjoo0813@gmail.com
Россия, Moscow, 119991
V. Dobrovolskiy
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Россия, Moscow
A. Stakheev
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Россия, Moscow
J. Abramova
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Россия, Moscow
A. Priadka
All-Russia Research Institute of Physicotechnical and Radio Engineering Measurements
Email: mongjoo0813@gmail.com
Россия, Moscow
A. Jaricov
Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
Email: mongjoo0813@gmail.com
Россия, Moscow
A. Nosyrev
National Research Center of Pharmacy, Sechenov First Moscow State Medical University
Email: mongjoo0813@gmail.com
Россия, Moscow
V. Rozhanets
Research Institute of Drug Abuse, Branch of Serbsky Federal Medical Research Center for Psychiatry and Drug Abuse
Email: mongjoo0813@gmail.com
Россия, Moscow
O. Shpigun
Department of Chemistry
Email: mongjoo0813@gmail.com
Россия, Moscow, 119991
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