Effect of Ascorbic Acid Isomeric Forms on Antibacterial Activity of Its Chitosan Salts


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Optical rotatory dispersion studies revealed water solutions of chitosan in L- and D-ascorbic acid to exhibit right rotation with anomalous dispersion and left rotation with normal dispersion, respectively. Microbiological investigation and transmission electron microscopy revealed the chitosan salt with D-ascorbic acid to cause deeper destructive changes than pure chitosan, which resulted in higher antibacterial activity against Staphylococcus aureus 209P and Escherichia coli 113-13.

About the authors

N. O. Gegel’

Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences

Author for correspondence.
Email: gegelno@yandex.ru
Russian Federation, Saratov

I. V. Zudina

Chernyshevsky Saratov State University

Email: gegelno@yandex.ru
Russian Federation, Saratov

O. N. Malinkina

Chernyshevsky Saratov State University

Email: gegelno@yandex.ru
Russian Federation, Saratov

A. B. Shipovskaya

Chernyshevsky Saratov State University

Email: gegelno@yandex.ru
Russian Federation, Saratov

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2018 Pleiades Publishing, Ltd.