The link of smoke and solar activity with human neoplasms

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Abstract

A review of the literature on the link of various types of smoke and solar activity with human neoplasms is presented. The significance of benign and malignant neoplasms in young children aged 0–4 years as an indicator of carcinogenic effects on the population is shown. Information about the oncogenic potential of all types of smoke, including exhaust gases, tobacco smoke and smoke from forest fires is provided. The special danger of vehicle exhaust gases is indicated in connection with the content of benzene, which is a proven human carcinogen. There is extensive evidence linking various types of smoke with the development of leukemia, Hodgkin's lymphoma, non-Hodgkin's lymphomas, multiple myeloma, retinoblastoma, neuroblastoma, hepatoblastoma, hemangiomas, and tumors of the central nervous system. Data on the connection between solar activity, in particular ultraviolet radiation, and the risk of leukemia, lymphomas as well as such neoplasms in young children aged 0–4 years as nephroblastoma, hemangioma, benign tumors and soft tissue sarcomas are highlighted. The possible role of geomagnetic field fluctuations in the genesis of hemoblastoses in children and adults is considered. The importance of ecologically determined oxidative stress in the realization of the oncogenic potential of environmental factors is shown. Possible measures for the prevention of neoplasms by reducing the intensity of human exposure to environmental factors, as well as methods for stopping oxidative stress, are considered. Recommendations on increasing the effectiveness of antioxidant protection by stimulating autophagy through the introducing various plant components, alkylcatechols into the diet, and correcting immunodeficiency with transfer factor are given.

About the authors

Sergey K. Pinaev

Far Eastern State Medical University

Author for correspondence.
Email: pinaev@mail.ru
ORCID iD: 0000-0003-0774-2376
Scopus Author ID: 56291097200
ResearcherId: J-5942-2018

M.D., Cand. Sci. (Med.), Assoc. Prof., Depart. of Oncology with a course of surgery and endoscopy of additional postgraduate education

Russian Federation, Khabarovsk, Russia

Alexey Ya. Chizhov

Peoples' Friendship University of Russia

Email: ma21@mail.ru
ORCID iD: 0000-0003-0542-1552
SPIN-code: 6701-2688
Scopus Author ID: 57205541090
ResearcherId: L-6981-2016

M.D., D. Sci. (Med.), Prof., Depart. of Human Ecology and Bioelementology, Institute of Ecology

Russian Federation, Moscow, Russia

Olga G. Pinaeva

Far Eastern State Medical University

Email: pinaeva_og@mail.ru
ORCID iD: 0000-0001-9676-845X
SPIN-code: 1678-3743
Scopus Author ID: 56290752700
ResearcherId: AAC-3445-2020

M.D., Cand. Sci. (Med.), Assoc. Prof., Depart. of Normal and Pathological Physiology

Russian Federation, Khabarovsk, Russia

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