Prevalence and biochemical markers of postpartum depression
- 作者: Reznik V.A.1, Kozyrko E.V.1, Ryazanova O.V.1, Aleksandrovich Y.S.1, Rukhliada N.N.1, Tapilskaya N.I.1
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隶属关系:
- Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
- 期: 卷 67, 编号 4 (2018)
- 页面: 19-29
- 栏目: Articles
- URL: https://bakhtiniada.ru/jowd/article/view/10351
- DOI: https://doi.org/10.17816/JOWD67419-29
- ID: 10351
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Postpartum depression (PPD) is a significant mental health and social problem. A prospective cohort single-center study was conducted in Saint Petersburg, Russia from March 2015 to October 2016 to assess the prevalence of PPD and possible serological markers associated with PPD. After exclusion of patients with a corresponding premorbid background and/or significant risk factors, prevalence rates were 9.6% on days P2 to P5. When comparing biochemical markers in patients with PPD (n = 37) and in healthy individuals (n = 72), a significant increase in the level of thyroid-stimulating hormone (3.36 ± 0.52 vs 1.98 ± 0.71 μIU/ml, p < 0.05), an increase in the level of marinobufagenin (0.928 ± 0.156 vs 0.462 ± 0.111 nM, p < 0.05), and a decrease in the activity of red-blood-cell Na+/K+-ATPase (1.68 ± 0.192 vs 2.39 ± 0.19 μM fn/ml/h, p < 0.03) were found.
作者简介
Vitaliy Reznik
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
编辑信件的主要联系方式.
Email: vitaliy-reznik@mail.ru
MD, PhD, Assistant Professor
俄罗斯联邦, Saint PetersburgElena Kozyrko
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Email: lenochka525@gmail.com
Senior Assistant of the Department of Pharmacology
俄罗斯联邦, Saint PetersburgOksana Ryazanova
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Email: oksanaryazanova@mail.ru
MD, PhD, Assistant Professor. The Department of Anesthesiology, Intensive Care and Emergency Pediatrics, Faculty of Retraining and Postgraduate Education
俄罗斯联邦, Saint PetersburgYuriy Aleksandrovich
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Email: Jalex1963@mail.ru
MD, PhD, DSci (Medicine), Professor, the Head of the Department of Anesthesiology, Intensive Care and Emergency Pediatrics, Faculty of Retraining and Postgraduate Education
俄罗斯联邦, Saint PetersburgNikolay Rukhliada
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Email: nickolasr@mail.ru
MD, PhD, DSci (Medicine), Professor, the Head of the Department of Obstetrics and Gynecology with the Course of Children and Adolescent Gynecology
俄罗斯联邦, Saint PetersburgNatalia Tapilskaya
Saint Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Email: tapnatalia@yandex.ru
MD, PhD, DSci (Medicine), Professor. The Department of Obstetrics and Gynecology with the Course of Children and Adolescent Gynecology
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