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Post a Comment Modeling of bleeding from varicose vein of esophagus in a laboratory animal
- Authors: Budarev V.N.1, Chekushin A.A.1
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Affiliations:
- Academician I.P. Pavlov Ryazan State Medical University
- Issue: Vol 39, No 3 (2022)
- Pages: 137-142
- Section: Biology and experimental medicine
- URL: https://bakhtiniada.ru/PMJ/article/view/104284
- DOI: https://doi.org/10.17816/pmj393137-142
- ID: 104284
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Abstract
Objective. To develop an accessible, easily reproducible, functional method for modeling bleeding from varicose veins of the esophagus based on the body of a laboratory animal.
Materials and methods. The work is based on an experiment carried out in the operating room of the vivarium of Ryazan State Medical University using laboratory animals – 12 domestic pigs of the Large White breed.
Results. In 10 cases out of 12, it was possible to successfully form changes in the animal's body, allowing to provoke bleeding from the dilated veins of the esophagus, damaging them with biopsy forceps during fibroesophagoscopy.
Conclusions. Creation of an experimental model of bleeding from varicose veins of the esophagus in the body of a domestic pig by dosed clamping of the hepato-duodenal ligament with a plastic clamp, which was followed by subsequent damage of the esophageal veins with biopsy forceps during fibroesophagoscopy, is technically feasible, reliable, and the model itself is quite functional.
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##article.viewOnOriginalSite##About the authors
Vadim N. Budarev
Academician I.P. Pavlov Ryazan State Medical University
Email: budarev.v@yandex.ru
ORCID iD: 0000-0001-5517-0005
Candidate of Medical Sciences, Associate Professor, Associate Professor of Department of General Surgery
Russian Federation, RyazanAlexander A. Chekushin
Academician I.P. Pavlov Ryazan State Medical University
Author for correspondence.
Email: budarev.v@yandex.ru
ORCID iD: 0000-0002-5977-8023
SPIN-code: 7226-9799
Candidate of Medical Sciences, Associate Professor, Department of General Surgery
Russian Federation, RyazanReferences
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