Мақаланы E-mail арқылы жіберу Strategies for Modulation of Pharmacokinetics of Recombinant Therapeutic Proteins
- Авторлар: Zvonova E.A.1,2, Tyurin A.A.2,3, Soloviev A.A.2, Goldenkova-Pavlova I.V.3
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Мекемелер:
- Generium International Biotechnological Center
- Timiryazev Russian State Agrarian University Moscow
- Timiryazev Institute of Plant Physiology
- Шығарылым: Том 8, № 2 (2018)
- Беттер: 124-141
- Бөлім: Article
- URL: https://bakhtiniada.ru/2079-0864/article/view/206769
- DOI: https://doi.org/10.1134/S2079086418020093
- ID: 206769
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The review describes current approaches to the optimization of pharmacokinetic properties of pharmaceutical proteins in order to achieve the maximum therapeutic effect. Examples of such technologies, including PEGylation, PEG mimetics, glycosylation, protein–protein fusion, and their advantages and limitations are discussed.
Авторлар туралы
E. Zvonova
Generium International Biotechnological Center; Timiryazev Russian State Agrarian University Moscow
Email: irengold58@gmail.com
Ресей, Vol’gincky, Vladimir oblast, 601125; Moscow, 127550
A. Tyurin
Timiryazev Russian State Agrarian University Moscow; Timiryazev Institute of Plant Physiology
Email: irengold58@gmail.com
Ресей, Moscow, 127550; Moscow, 127276
A. Soloviev
Timiryazev Russian State Agrarian University Moscow
Email: irengold58@gmail.com
Ресей, Moscow, 127550
I. Goldenkova-Pavlova
Timiryazev Institute of Plant Physiology
Хат алмасуға жауапты Автор.
Email: irengold58@gmail.com
Ресей, Moscow, 127276
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