电邮这篇文章 Strategies for Modulation of Pharmacokinetics of Recombinant Therapeutic Proteins
- 作者: Zvonova E.A.1,2, Tyurin A.A.2,3, Soloviev A.A.2, Goldenkova-Pavlova I.V.3
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隶属关系:
- Generium International Biotechnological Center
- Timiryazev Russian State Agrarian University Moscow
- Timiryazev Institute of Plant Physiology
- 期: 卷 8, 编号 2 (2018)
- 页面: 124-141
- 栏目: Article
- URL: https://bakhtiniada.ru/2079-0864/article/view/206769
- DOI: https://doi.org/10.1134/S2079086418020093
- ID: 206769
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详细
The review describes current approaches to the optimization of pharmacokinetic properties of pharmaceutical proteins in order to achieve the maximum therapeutic effect. Examples of such technologies, including PEGylation, PEG mimetics, glycosylation, protein–protein fusion, and their advantages and limitations are discussed.
作者简介
E. Zvonova
Generium International Biotechnological Center; Timiryazev Russian State Agrarian University Moscow
Email: irengold58@gmail.com
俄罗斯联邦, Vol’gincky, Vladimir oblast, 601125; Moscow, 127550
A. Tyurin
Timiryazev Russian State Agrarian University Moscow; Timiryazev Institute of Plant Physiology
Email: irengold58@gmail.com
俄罗斯联邦, Moscow, 127550; Moscow, 127276
A. Soloviev
Timiryazev Russian State Agrarian University Moscow
Email: irengold58@gmail.com
俄罗斯联邦, Moscow, 127550
I. Goldenkova-Pavlova
Timiryazev Institute of Plant Physiology
编辑信件的主要联系方式.
Email: irengold58@gmail.com
俄罗斯联邦, Moscow, 127276
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