Synthesis of New Guanidine-Containing Amphiphiles and Their Pyrene Analog for Liposomal Delivery Systems and Visualization in Target Cells

Resumo

New cationic amphiphiles with a guanidine head group have been synthesized starting from lipoamino acids with the goal of creating drug and genetic material delivery systems. Their analog containing a pyrene fragment has also been obtained as a potential agent for visualization of liposome transport in various cells.