Synthesis and Properties of Aminomethoxy Derivatives of 1-Phenoxy-3-(propylsulfanyl)propane

Resumo

The condensation of 1-phenoxy-3-(propylsulfanyl)propan-2-ol with formaldehyde and secondary aliphatic and heterocyclic amines afforded new aminomethoxy derivatives of 1-phenoxy-3-(propylsulfanyl)- propane in 69–77% yields. The product structure was confirmed by elemental analyses and IR and ¹H and ¹³C NMR spectra. The synthesized compounds were assayed as antiseptics against bacteria and fungi and were shown to be more efficient antimicrobial agents than those currently used in medicine.