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Synthesis of 1-(arylsulfonyl)pyrrolidines from phenols and 1-[(4-chlorophenyl)sulfonyl]-2-ethoxypyrrolidine


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Abstract

Acid-catalyzed reaction of 1-[(4-chlorophenyl)sulfonyl]-2-ethoxypyrrolidine with phenols leads to the formation of new 1-(arylsulfonyl)pyrrolidines. The reaction proceeds under mild conditions and may be used as a convenient method for the synthesis of pyrrolidine-1-sulfonylarene derivatives containing a phenol fragment in the position 2.

About the authors

A. V. Smolobochkin

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: agazizov@iopc.ru
Russian Federation, ul. Academika Arbuzova 8, Kazan, 420088

E. A. Anikina

Kazan National Research Technological University

Email: agazizov@iopc.ru
Russian Federation, Kazan

A. S. Gazizov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Author for correspondence.
Email: agazizov@iopc.ru
Russian Federation, ul. Academika Arbuzova 8, Kazan, 420088

A. R. Burilov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: agazizov@iopc.ru
Russian Federation, ul. Academika Arbuzova 8, Kazan, 420088

M. A. Pudovik

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: agazizov@iopc.ru
Russian Federation, ul. Academika Arbuzova 8, Kazan, 420088

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