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Yamaguchi Esterification in the Synthetic Approaches to Precursors of Epothilone D Analogs


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Resumo

Coupling of previously synthesized chiral building blocks via Yamaguchi esterification has been studied with the goal of obtaining epothilone D isosteres. Some peculiar features of the Yamaguchi esterification stage have been revealed, which are related to the reactivity and molecular structure of the initial acid and alcohol components.

Sobre autores

R. Valeev

Ufa Institute of Organic Chemistry, Ufa Federal Research Center

Autor responsável pela correspondência
Email: rusl0@yandex.ru
Rússia, Ufa, Bashkortostan

G. Sunagatullina

Ufa Institute of Organic Chemistry, Ufa Federal Research Center

Email: rusl0@yandex.ru
Rússia, Ufa, Bashkortostan

M. Miftakhov

Ufa Institute of Organic Chemistry, Ufa Federal Research Center

Email: rusl0@yandex.ru
Rússia, Ufa, Bashkortostan

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