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Reactions of 1,2,4-trichlorotrifluorobenzene with nucleophiles


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Abstract

1,2,4-Trichlorotrifluorobenzene reacted with potassium hydrogen sulfide, potassium hydroxide, sodium isopropoxide, liquid ammonia, and ethyl cyanoacetate via nucleophilic substitution of one fluorine atom with predominant formation of the isomer in which the new substituent replaced fluorine atom in the 5-position.

About the authors

P. V. Nikul’shin

Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch

Author for correspondence.
Email: platonov@nioch.nsc.ru
Russian Federation, pr. Akademika Lavrent’eva 9, Novosibirsk, 630090

A. M. Maksimov

Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch

Email: platonov@nioch.nsc.ru
Russian Federation, pr. Akademika Lavrent’eva 9, Novosibirsk, 630090

V. E. Platonov

Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch

Email: platonov@nioch.nsc.ru
Russian Federation, pr. Akademika Lavrent’eva 9, Novosibirsk, 630090

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