Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its transformation into amino alcohols containing an indan-1,3-dione fragment
- Authors: Popov L.D.1, Suzdalev K.F.1
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Affiliations:
- Southern Federal University
- Issue: Vol 52, No 6 (2016)
- Pages: 844-847
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/214523
- DOI: https://doi.org/10.1134/S1070428016060142
- ID: 214523
Cite item
Abstract
A procedure for the synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde was developed and optimized. Its reaction with indan-1,3-dione, followed by treatment with amines, afforded 1,2-amino alcohols containing an indole fragment.
About the authors
L. D. Popov
Southern Federal University
Author for correspondence.
Email: ldpopov@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
K. F. Suzdalev
Southern Federal University
Email: ldpopov@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090
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