Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its transformation into amino alcohols containing an indan-1,3-dione fragment


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Abstract

A procedure for the synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde was developed and optimized. Its reaction with indan-1,3-dione, followed by treatment with amines, afforded 1,2-amino alcohols containing an indole fragment.

About the authors

L. D. Popov

Southern Federal University

Author for correspondence.
Email: ldpopov@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090

K. F. Suzdalev

Southern Federal University

Email: ldpopov@mail.ru
Russian Federation, ul. Zorge 7, Rostov-on-Don, 344090

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