Email this article A Simple Efficient Click Synthesis of Novel Crown Ethers Containing 1,2,3-Triazole Moieties
- Authors: Elamari H.1, Ouerghui A.2,3, Ammari F.3, Girard C.1
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Affiliations:
- Unit of Chemical and Biological Technologies for Health, UMR 8258 CNRS/U1022 Inserm, National Chemical Engineering Institute in Paris
- Unit of Functional Physiology and Valorization ofBioresources (UR17ES27), Higher Institute of Biotechnology of Beja
- Laboratory of Organic Chemistry and Applications (Unit 05/UR/12-05), Faculty of Sciences of Bizerte
- Issue: Vol 55, No 11 (2019)
- Pages: 1785-1790
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/221420
- DOI: https://doi.org/10.1134/S1070428019110228
- ID: 221420
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Abstract
Novel crown ether derivative containing 1,4-disubstituted-1,2,3-triazole moieties were synthesized. At the first step of the synthesis 4,13-diaza-18-crown-6 and 4-aminobenzo-15-crown-5 were converted into terminal alkynes, which were then subjected to copper(I)-catalyzed alkyne-azide coupling (CuAAC) in methylene chloride. This coupling reaction was performed according to the concept of click chemistry, using an Amberlyst A-21-supported copper(I) iodide catalyst.
About the authors
H. Elamari
Unit of Chemical and Biological Technologies for Health, UMR 8258 CNRS/U1022 Inserm, National Chemical Engineering Institute in Paris
Email: ouerghiabid@gmail.com
France, 11 rue Pierre et Marie Curie, Paris, 75005
A. Ouerghui
Unit of Functional Physiology and Valorization ofBioresources (UR17ES27), Higher Institute of Biotechnology of Beja; Laboratory of Organic Chemistry and Applications (Unit 05/UR/12-05), Faculty of Sciences of Bizerte
Author for correspondence.
Email: ouerghiabid@gmail.com
Tunisia, Beja, 9000; Bizerte, 7021
F. Ammari
Laboratory of Organic Chemistry and Applications (Unit 05/UR/12-05), Faculty of Sciences of Bizerte
Email: ouerghiabid@gmail.com
Tunisia, Bizerte, 7021
C. Girard
Unit of Chemical and Biological Technologies for Health, UMR 8258 CNRS/U1022 Inserm, National Chemical Engineering Institute in Paris
Email: ouerghiabid@gmail.com
France, 11 rue Pierre et Marie Curie, Paris, 75005
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