Отправить статью по E-mail Substituted 2-(2-Arylethenyl)quinazolines. Synthesis and Structure
- Авторы: Harutyunyan A.A.1,2, Gukasyan G.T.1, Panosyan H.A.2, Tamazyan R.A.2, Ayvazyan A.G.2, Danagulyan G.G.1,2
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Учреждения:
- Russian Armenian (Slavic) University
- Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Выпуск: Том 55, № 9 (2019)
- Страницы: 1363-1369
- Раздел: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/221169
- DOI: https://doi.org/10.1134/S107042801909015X
- ID: 221169
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Аннотация
The reaction of 2-methyl-4H-3,1-benzoxazin-4-one and its 6-iodo derivatives with a number of amines in polyphosphoric acid afforded 3- and 3,6-substituted 2-methylquinazolin-4(3H)-ones. The latter reacted with aromatic and heterocyclic aldehydes under solvent-free conditions to give 2-[(E)-2-arylethenyl]-quinazolin-4(3H)-ones. The structure of the synthesized compounds was confirmed by two-dimensional 1H–1H NOESY data and X-ray analysis.
Об авторах
A. Harutyunyan
Russian Armenian (Slavic) University; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Автор, ответственный за переписку.
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan; Yerevan
G. Gukasyan
Russian Armenian (Slavic) University
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan
H. Panosyan
Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan
R. Tamazyan
Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan
A. Ayvazyan
Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan
G. Danagulyan
Russian Armenian (Slavic) University; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Армения, Yerevan; Yerevan
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