Synthesis of New Sulfur-Substituted Pentacyclic 1,2,4-Triazolopyrimidine Derivatives

Abstract

Pentacyclic heterocyclic compounds containing a 1,2,4-triazole ring have been synthesized from [5-(2-methylpropyl)-1,2,3,4-tetrahydropyrimido[4′,5′: 4,5]thieno[2,3-c]isoquinolin-8-yl]hydrazine. The synthesized [1,2,4]triazolo[4,3-c]pyrimidine derivatives have been found to undergo Dimroth rearrangement in both acidic and basic media.