Email this article Acid-Catalyzed Heterocyclization of Trialkylnaphthazarin Thioglucosides in Angular Quinone-Carbohydrate Tetracycles
- Authors: Sabutskii Y.E.1, Denisenko V.A.1, Popov R.S.1, Polonik S.G.1
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Affiliations:
- Elyakov Pacific Institute of Bioorganic Chemistry
- Issue: Vol 55, No 2 (2019)
- Pages: 147-151
- Section: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/219798
- DOI: https://doi.org/10.1134/S1070428019020040
- ID: 219798
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Abstract
Tetracyclic naphthoquinone-carbohydrate conjugates with an angular-fused heterocycle were obtained for the first time by the intramolecular condensation of naphthazarin thioglucosides in a mixture of n-butanol and methanesulfonic acid under reflux. The competing reaction is hydrolysis of the thioglucosidic bond with formation of trialkylmercaptonaphthazarins.
About the authors
Y. E. Sabutskii
Elyakov Pacific Institute of Bioorganic Chemistry
Email: sergpol@piboc.dvo.ru
Russian Federation, pr. 100 let Vladivostoku 159, Vladivostok, 690022
V. A. Denisenko
Elyakov Pacific Institute of Bioorganic Chemistry
Email: sergpol@piboc.dvo.ru
Russian Federation, pr. 100 let Vladivostoku 159, Vladivostok, 690022
R. S. Popov
Elyakov Pacific Institute of Bioorganic Chemistry
Email: sergpol@piboc.dvo.ru
Russian Federation, pr. 100 let Vladivostoku 159, Vladivostok, 690022
S. G. Polonik
Elyakov Pacific Institute of Bioorganic Chemistry
Author for correspondence.
Email: sergpol@piboc.dvo.ru
Russian Federation, pr. 100 let Vladivostoku 159, Vladivostok, 690022
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