Synthesis of N-Substituted Methyl 4H-Thieno[3,2-b]pyrrole-5-carboxylates


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Abstract

The alkylation of methyl 4H-thieno[3,2-b]pyrrole-5-carboxylate with methyl iodide and allyl, propargyl, and benzyl bromides in the presence of sodium hydride in THF afforded the corresponding N-substituted derivatives. Some reactions of the alkylation products were studied.

About the authors

S. A. Torosyan

Ufa Institute of Chemistry

Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

F. A. Gimalova

Ufa Institute of Chemistry

Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

V. V. Zagitov

Bashkir State University

Email: bioreg@anrb.ru
Russian Federation, ul. Zaki Validi 32, Ufa, 450076 Bashkortostan

A. S. Erastov

Ufa Institute of Chemistry

Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

M. S. Miftakhov

Ufa Institute of Chemistry

Author for correspondence.
Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

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