o-Acylbenzonitriles: Synthesis and Heterocyclization under Acid Hydrolysis of the Cyano Group
- Авторы: Mochalov S.S.1, Fedotov A.N.1, Trofimova E.V.1, Zefirov N.S.1
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Учреждения:
- Faculty of Chemistry
- Выпуск: Том 54, № 3 (2018)
- Страницы: 403-413
- Раздел: Article
- URL: https://bakhtiniada.ru/1070-4280/article/view/217280
- DOI: https://doi.org/10.1134/S1070428018030065
- ID: 217280
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Аннотация
2-Cyanobenzophenones were synthesized by reaction of 2-bromobenzophenones with copper(I) cyanide in DMF, and their transformations involving acid hydrolysis of the cyano group were studied. Reactions of o-benzoylbenzonitriles with trifluoroacetic acid in the presence or in the absence of sulfuric acid afforded 3-hydroxyphthalimidines in high yields. Under analogous conditions, benzonitriles having no acyl group in the ortho position were converted to the corresponding benzamides. 2-Cyanobenzophenones reacted with sulfuric acid in the absence of trifluoroacetic acid to give only substituted anthraquinones.
Об авторах
S. Mochalov
Faculty of Chemistry
Email: fed@org.chem.msu.ru
Россия, Leninskie gory 1, Moscow, 119991
A. Fedotov
Faculty of Chemistry
Автор, ответственный за переписку.
Email: fed@org.chem.msu.ru
Россия, Leninskie gory 1, Moscow, 119991
E. Trofimova
Faculty of Chemistry
Email: fed@org.chem.msu.ru
Россия, Leninskie gory 1, Moscow, 119991
N. Zefirov
Faculty of Chemistry
Email: fed@org.chem.msu.ru
Россия, Leninskie gory 1, Moscow, 119991
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