Synthesis of 2,5-diaryl-1,3-oxazoles containing a carbamate group


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

Acetophenones containing a methoxycarbonylamino group in position 2, 3, or 4 of the aromatic ring reacted with phenylglycine in the presence of 2 equiv of iodine and 0.5 equiv of sulfanilic acid in DMSO at 100°C for 6 h to give methyl [2(3,4)-(2-phenyl-1,3-oxazol-5-yl)phenyl]carbamates. The reaction was presumed to involve intermediate formation of methyl [(iodoacetyl)phenyl]carbamate. This was confirmed by the isolation of methyl [2-(iodoacetyl)phenyl]carbamate in the reaction of methyl (2-acetylphenyl)carbamate with iodine in glacial acetic acid and its subsequent transformation to methyl [2-(2-phenyl-1,3-oxazol-5-yl)-phenyl]carbamate.

作者简介

A. Velikorodov

Astrakhan State University

编辑信件的主要联系方式.
Email: avelikorodov@mail.ru
俄罗斯联邦, pl. Shaumyana 1, Astrakhan, 414000

E. Shustova

Astrakhan State University

Email: avelikorodov@mail.ru
俄罗斯联邦, pl. Shaumyana 1, Astrakhan, 414000

S. Nosachev

Astrakhan State University

Email: avelikorodov@mail.ru
俄罗斯联邦, pl. Shaumyana 1, Astrakhan, 414000

补充文件

附件文件
动作
1. JATS XML

版权所有 © Pleiades Publishing, Ltd., 2017