Synthesis of (2R,4R)-2-alkyl-3-(2-mercaptobenzoyl)thiazolidine-4-carboxylic acids


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详细

Basing on natural amino acid L-cysteine, commercially available aliphatic aldehydes, 2-acetylsulfanylbenzoyl chloride and 2,2′-disulfandiyldibenzoyl dichloride a synthesis was developed of (2R,4R)-2-alkyl-3-(2-mercaptobenzoyl)thiazolidine-4-carboxylic acids, potential antihypertensive compounds, inhibitors of angiotensin transforming enzyme.

作者简介

А. Ershov

Institute of Macromolecular Compounds

编辑信件的主要联系方式.
Email: ershov305@mail.ru
俄罗斯联邦, V.O., Bol’shoi pr. 31, St. Petersburg, 199004

I. Lagoda

R&D Test Center (of Medico-Biological Protection), State R&D Institute of Military Medicine

Email: ershov305@mail.ru
俄罗斯联邦, St. Petersburg

D. Nasledov

Institute of Macromolecular Compounds

Email: ershov305@mail.ru
俄罗斯联邦, V.O., Bol’shoi pr. 31, St. Petersburg, 199004

M. Vasil’eva

Institute of Macromolecular Compounds

Email: ershov305@mail.ru
俄罗斯联邦, V.O., Bol’shoi pr. 31, St. Petersburg, 199004

L. Kuleshova

Ryazan Medical University

Email: ershov305@mail.ru
俄罗斯联邦, Ryazan

L. Pavlova

R&D Test Center (of Medico-Biological Protection), State R&D Institute of Military Medicine

Email: ershov305@mail.ru
俄罗斯联邦, St. Petersburg

A. Yakimanskii

Institute of Macromolecular Compounds; St. Petersburg State University

Email: ershov305@mail.ru
俄罗斯联邦, V.O., Bol’shoi pr. 31, St. Petersburg, 199004; St. Petersburg

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