Alternative synthesis of alverine


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Abstract

An efficient synthesis of alverine via iron-catalyzed double cross-coupling of (2E)-3-chloro-N-[(2E)-3-chloroprop-2-en-1-yl]-N-ethylprop-2-en-1-amine with phenylmagnesium bromide is described.

About the authors

R. N. Shakhmaev

Ufa State Petroleum Tecnological University

Author for correspondence.
Email: biochem@rusoil.net
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062

A. Sh. Sunagatullina

Ufa State Petroleum Tecnological University

Email: biochem@rusoil.net
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062

V. V. Zorin

Ufa State Petroleum Tecnological University

Email: biochem@rusoil.net
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062

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