Domino reactions of pyrazol-5-amines with arylglyoxals and malononitrile

O. N. Petrova; V. V. Lipson; L. L. Zamigajlo; M. G. Shirobokova; V. I. Musatov; D. A. Dmitrienko

doi:10.1134/S1070428016080121

Domino reactions of pyrazol-5-amines with arylglyoxals and malononitrile

Authors: Petrova O.N.¹, Lipson V.V.¹^,2^,3, Zamigajlo L.L.¹, Shirobokova M.G.¹, Musatov V.I.¹, Dmitrienko D.A.³
Affiliations:
1. Research and Development Complex “Institute of Single Crystals”
2. Danilevskii Institute of the Endocrinal Pathology Problems
3. Karazin Kharkiv National University
Issue: Vol 52, No 8 (2016)
Pages: 1168-1172
Section: Article
URL: https://bakhtiniada.ru/1070-4280/article/view/214831
DOI: https://doi.org/10.1134/S1070428016080121
ID: 214831

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Abstract
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Abstract

Domino reactions of 3-methylpyrazol-5-amine and 1-phenyl-3-methylpyrazol-5-amine with arylglyoxal hydrates and malononitrile in alcohol proceed regioselectively and lead to the formation of 6-aminopyrazolo[3,4-b]pyridine-5-carbonitrile.

About the authors

O. N. Petrova

Research and Development Complex “Institute of Single Crystals”

Email: lipson@ukr.net
Ukraine, Kharkiv

V. V. Lipson

Research and Development Complex “Institute of Single Crystals”; Danilevskii Institute of the Endocrinal Pathology Problems; Karazin Kharkiv National University

Author for correspondence.
Email: lipson@ukr.net
Ukraine, Kharkiv; ul. Alchevskikh 10, Kharkiv, 61002; Kharkiv