Using gamma rays to inactivate African swine fever virus


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The results of the study of potential ability of gamma rays (60Co, PX-gamma-30) to inactivate African swine fever virus in porcine hyperimmune sera, cell culture, and rawhide obtained from animals with African swine fever are discussed. Upon exposure to gamma rays in the doses varying from 5 kGy to 40 kGy, the virus more readily lost its infectivity than its antigenicity, as was demonstrated by the hemadsorption test, inhibition assay, immunoblotting, immunofluorescence, electron microscopy, and the biological assay involving pigs.

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V. Boudarkov

National Research Institute of Veterinary Virology and Microbiology

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Email: budarkovva@yandex.ru
俄罗斯联邦, Vladimir oblast, 601125

A. Sereda

National Research Institute of Veterinary Virology and Microbiology

Email: budarkovva@yandex.ru
俄罗斯联邦, Vladimir oblast, 601125

O. Carpov

National Research Institute of Veterinary Virology and Microbiology

Email: budarkovva@yandex.ru
俄罗斯联邦, Vladimir oblast, 601125

V. Ponomarev

National Research Institute of Veterinary Virology and Microbiology

Email: budarkovva@yandex.ru
俄罗斯联邦, Vladimir oblast, 601125

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