Asymmetric Ir-catalyzed hydrogenation of 1,3-dihydro-2H-1,5-benzodiazepin-2-ones using phosphoramidites
- 作者: Sokolovskaya M.V.1, Lyubimov S.E.1, Mikhel I.S.2, Birin K.P.2, Davankov V.A.1
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隶属关系:
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
- 期: 卷 67, 编号 2 (2018)
- 页面: 260-264
- 栏目: Full Articles
- URL: https://bakhtiniada.ru/1066-5285/article/view/242116
- DOI: https://doi.org/10.1007/s11172-018-2068-9
- ID: 242116
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详细
A series of phosphoramidite ligands was tested in the asymmetric hydrogenation of 4-arylsubstituted 1,3-dihydro-2H-benzodiazepine-2-ones and up to 52% ee was achieved. The effects of various factors (solvents, hydrogen pressure, and addition of phosphine ligands) on the hydrogenation were studied.
作者简介
M. Sokolovskaya
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: lssp452@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
S. Lyubimov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: lssp452@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
I. Mikhel
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
Email: lssp452@mail.ru
俄罗斯联邦, 31/4 Leninsky prosp., Moscow, 119071
K. Birin
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences
Email: lssp452@mail.ru
俄罗斯联邦, 31/4 Leninsky prosp., Moscow, 119071
V. Davankov
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: lssp452@mail.ru
俄罗斯联邦, 28 ul. Vavilova, Moscow, 119991
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