CHARACTERISTICS OF SECRETORY IMMUNE SYSTEM IN WOMEN AND MEN INFECTED WITH HPV HIGH-RISK TYPES, DEPENDING ON VIRAL LOAD
- Authors: Telesheva L.F.1, Lysenko O.V.1, Markeeva D.A.1, Zotova M.A.1
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Affiliations:
- South Ural state medical University
- Issue: Vol 20, No 3 (2017)
- Pages: 524-526
- Section: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/119924
- ID: 119924
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Abstract
Human papillomavirus infection (HPV infection) is equally widespread among women and among men. The purpose of this study was to determine the levels of main immunological parameters of the secretory immune system in women and men from 38 couples infected with HPV of high oncogenic risk, with different types of viral load. The object of the study in women was cervical mucus, men - ejaculate. Results. Both women and men from couples with HPV each time a viral load was determined by the increase in the number of IL-2 and IL-8, decrease of IL-4 and TNF-α. When significant concentrations of HPV DNA in women they have increased the number of sIgA, men elevated were IL-φ, IFN-α and IFN-γ.
About the authors
L. F. Telesheva
South Ural state medical University
Author for correspondence.
Russian Federation
O. V. Lysenko
South Ural state medical UniversityRussian Federation
D. A. Markeeva
South Ural state medical UniversityRussian Federation
M. A. Zotova
South Ural state medical UniversityRussian Federation
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