CHARACTERISTICS OF SECRETORY IMMUNE SYSTEM IN WOMEN AND MEN INFECTED WITH HPV HIGH-RISK TYPES, DEPENDING ON VIRAL LOAD
- 作者: Telesheva L.F.1, Lysenko O.V.1, Markeeva D.A.1, Zotova M.A.1
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隶属关系:
- South Ural state medical University
- 期: 卷 20, 编号 3 (2017)
- 页面: 524-526
- 栏目: Articles
- URL: https://bakhtiniada.ru/1028-7221/article/view/119924
- ID: 119924
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详细
Human papillomavirus infection (HPV infection) is equally widespread among women and among men. The purpose of this study was to determine the levels of main immunological parameters of the secretory immune system in women and men from 38 couples infected with HPV of high oncogenic risk, with different types of viral load. The object of the study in women was cervical mucus, men - ejaculate. Results. Both women and men from couples with HPV each time a viral load was determined by the increase in the number of IL-2 and IL-8, decrease of IL-4 and TNF-α. When significant concentrations of HPV DNA in women they have increased the number of sIgA, men elevated were IL-φ, IFN-α and IFN-γ.
作者简介
L. Telesheva
South Ural state medical University
编辑信件的主要联系方式.
俄罗斯联邦
O. Lysenko
South Ural state medical University俄罗斯联邦
D. Markeeva
South Ural state medical University俄罗斯联邦
M. Zotova
South Ural state medical University俄罗斯联邦
参考
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- Лысенко О. В., Телешева Л. Ф., Троянова А. В. Папилломавирусная инфекция у семейных пар: заметки к теме // Современные проблемы дерматовенерологии, иммунологии и врачебной косметологии. 2013. Т. 8.№ 3 (26). С. 49-55.
- Телешева Л. Ф., Маркова В. А., Лысенко О. В., Троянова А. В. Оценка иммунологической эффективности лечения изопринозином у семейных пар, инфицированных ВПЧ // Рос. иммунол. журн.-2015.- Т. 9 (18), № 1(1) - С. 183-184.
- Siegel E. M., Patel N., Lu B., Lee J. H., et al. Biomarkers of oxidant load and type-specific clearance of prevalent oncogenic human papillomavirus infection: markers of immune response? //Int J Cancer. 2012. 131(1). P 219-28.
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