电邮这篇文章 Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma
- 作者: Sokolova A.S.1,2, Yarovaya O.I.1,2, Nefedov A.A.1,2, Salakhutdinov N.F.1,2
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隶属关系:
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences
- Novosibirsk State University
- 期: 卷 51, 编号 12 (2018)
- 页面: 1102-1105
- 栏目: Structure of Chemical Compounds, Methods of Analysis and Process Control
- URL: https://bakhtiniada.ru/0091-150X/article/view/244929
- DOI: https://doi.org/10.1007/s11094-018-1748-y
- ID: 244929
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详细
A new GC-MS method for determining an antiviral agent (camphecin) in blood plasma was developed. Sample preparation consisted of precipitating proteins using MeOH. The method was validated for selectivity, calibration curve, accuracy, precision, limit of quantitation, carryover, and stability. The analytical range was 0.1 – 2 μg/mL. The method could be used for pharmacokinetic studies.
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作者简介
A. Sokolova
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences; Novosibirsk State University
编辑信件的主要联系方式.
Email: a.s.sokolova@mail.ru
俄罗斯联邦, 9 Pr. Akad. Lavrent’eva, Novosibirsk, 630090; 2 Pirogova St., Novosibirsk, 630090
O. Yarovaya
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences; Novosibirsk State University
Email: a.s.sokolova@mail.ru
俄罗斯联邦, 9 Pr. Akad. Lavrent’eva, Novosibirsk, 630090; 2 Pirogova St., Novosibirsk, 630090
A. Nefedov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences; Novosibirsk State University
Email: a.s.sokolova@mail.ru
俄罗斯联邦, 9 Pr. Akad. Lavrent’eva, Novosibirsk, 630090; 2 Pirogova St., Novosibirsk, 630090
N. Salakhutdinov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences; Novosibirsk State University
Email: a.s.sokolova@mail.ru
俄罗斯联邦, 9 Pr. Akad. Lavrent’eva, Novosibirsk, 630090; 2 Pirogova St., Novosibirsk, 630090
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