Email this article DETERMINATION OF ANTIBIOTICS IN WASTEWATER USING AMPEROMETRIC SENSORS
- Authors: Gam P.T.1,2, Tertyshnikova O.A.1, Zyablov A.N.1, Vybornyi A.Y.1, Litvinova N.A.3
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Affiliations:
- Voronezh State University, Faculty of Chemistry
- Hanoi University of Business and Technology, Faculty of Pharmacy
- OOO RVC-Voronezh
- Issue: Vol 80, No 9 (2025)
- Pages: 996-1002
- Section: ORIGINAL ARTICLES
- Submitted: 10.09.2025
- URL: https://bakhtiniada.ru/0044-4502/article/view/308734
- DOI: https://doi.org/10.31857/S0044450225090085
- EDN: https://elibrary.ru/bugbcz
- ID: 308734
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Abstract
Sensors for the amperometric determination of the antibiotics Cefur and Ceftr in aqueous solutions have been developed. The sensor electrodes were coated with molecularly imprinted polymers (MIPs). To evaluate selectivity and recognition capabilities toward target molecules, the imprinting factor and selectivity coefficient were determined. The imprinting factors were 5.3 for MIP-Cefur and 5.1 for MIP-Ceftr. The results showed that MIPs have greater selectivity and target recognition ability compared to non-imprinted polymers. The antibiotics were quantified in aqueous solutions using the calibration curve method. The experimentally determined detection ranges for Cefur and Ceftr were from 1.0 × 10–⁵ to 0.1 g/L. Detection limits were 3.5 × 10–⁶ g/L for Cefur and 6.6 × 10–⁶ g/L for Ceftr. The MIP-modified sensors were successfully tested in wastewater samples. The results demonstrate the feasibility of using amperometric sensors based on MIPs for detecting sodium cefuroxime and sodium ceftriaxone in model and real wastewater systems.
About the authors
P. T. Gam
Voronezh State University, Faculty of Chemistry; Hanoi University of Business and Technology, Faculty of Pharmacy
Email: alex-n-z@yandex.ru
Voronezh, Universitskaya Sq., 1, 394018, Russia; Hanoi, HAI BA TRUNG, 124, Vinh Tuy, 11600, Vietnam
O. A. Tertyshnikova
Voronezh State University, Faculty of ChemistryVoronezh, Universitskaya Sq., 1, 394018, Russia
A. N. Zyablov
Voronezh State University, Faculty of Chemistry
Email: alex-n-z@yandex.ru
Voronezh, Universitskaya Sq., 1, 394018, Russia
A. Y. Vybornyi
Voronezh State University, Faculty of ChemistryVoronezh, Universitskaya Sq., 1, 394018, Russia
N. A. Litvinova
OOO RVC-VoronezhVoronezh, 21, Antokolskogo St., 394062, Russia
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