Iontophoretic transport of associates based on porous Keplerate-type cluster polyoxometalate Mo72Fe30 and containing biologically active substances
- Autores: Ostroushko A.A.1, Gagarin I.D.1, Tonkushina M.O.1, Grzhegorzhevskii K.V.1, Danilova I.G.1,2, Gette I.F.1,2, Kim G.A.3
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Afiliações:
- Research Institute of Physics and Applied Mathematics
- Institute of Immunology and Physiology, Ural Branch
- Postovsky Institute of Organic Synthesis, Ural Branch
- Edição: Volume 91, Nº 9 (2017)
- Páginas: 1811-1815
- Seção: Colloid Chemistry and Electrochemistry
- URL: https://bakhtiniada.ru/0036-0244/article/view/169708
- DOI: https://doi.org/10.1134/S0036024417090230
- ID: 169708
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Resumo
The possibility of iontophoretic transport through the native membranes of biologically active substances (vitamin B1 and insulin) associated with porous clusters Mo72Fe30 polyoxometalate of the Keplerate type is demonstrated for the first time in an experimental setup. The diffusion coefficient is estimated. The possibility of transferring Keplerate ions with a protective coating of biocompatible polymer polyvinylpyrrolidone is also shown.
Sobre autores
A. Ostroushko
Research Institute of Physics and Applied Mathematics
Autor responsável pela correspondência
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002
I. Gagarin
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002
M. Tonkushina
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002
K. Grzhegorzhevskii
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002
I. Danilova
Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002; Yekaterinburg, 620049
I. Gette
Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620002; Yekaterinburg, 620049
G. Kim
Postovsky Institute of Organic Synthesis, Ural Branch
Email: alexander.ostroushko@urfu.ru
Rússia, Yekaterinburg, 620990
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