Positron Annihilation Doppler Broadening Studies on Ruthenium(III) Antibiotic Sulfa-Drug Complexes


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Abstract

The structural difference between five sulfa drug compounds and their Ru(III) complexes with 1 : 2 molar ratio were examined using the positron annihilation Doppler broadening (PADB) spectroscopy. The PADB measurements were performed with a HPGe γ-ray spectrometer. The change of defect structure due to the Ru(III) complexation process was confirmed. The correlation between the DP line-shape parameters (S and W) and the previous reported results of the microanalytical, physicochemical, biological and positron annihilation lifetime (PAL) measurements of sulfa drug Ru(III) complexes were examined.

About the authors

Foziah A. Al-Saif

College of Science, Princess Nourah bint Abdulrahman University, Department of Chemistry

Email: msrefat@yahoo.com
Saudi Arabia, City

Khuloud A. Alibrahim

College of Science, Princess Nourah bint Abdulrahman University, Department of Chemistry

Email: msrefat@yahoo.com
Saudi Arabia, City

T. Sharshar

Physics Department, Faculty of Science, Kafrelsheikh University

Email: msrefat@yahoo.com
Egypt, Kafr El-Sheikh

Ahmed M. Naglah

Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC),
College of Pharmacy, King Saud University; Peptide Chemistry Department, Chemical Industries Research Division,
National Research Centre

Email: msrefat@yahoo.com
Saudi Arabia, Riyadh, 11451; Cairo, 12622-Dokki

Moamen S. Refat

Chemistry Department, Faculty of Science, Port Said University; Department of Chemistry, Faculty of Science, Taif University

Author for correspondence.
Email: msrefat@yahoo.com
Egypt, Port Said; P.O. Box 888 Zip Code, Al-Hawiah, Taif, 21974

Abdel Majid A. Adam

Department of Chemistry, Faculty of Science, Taif University

Email: msrefat@yahoo.com
Saudi Arabia, P.O. Box 888 Zip Code, Al-Hawiah, Taif, 21974

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