Electrochemical method for producing radionuclide Lu-177 with high specific activity


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A modified method for the isolation of radionuclide 177Lu obtained from a Yb-176 target irradiated with thermal neutrons is proposed. The method consists of the combination of two electrochemical processes— cementation of ytterbium acetate–chloride solution to sodium amalgam and subsequent electrolysis of the ytterbium solution in a separate electrolytic cell without adjusting the solution. The electrochemical setup consisting of two cells gives the purification factor of 177Lu from ytterbium at a level of 105–106, which allows using 177Lu of such quality for labeling bioorganic molecules.

Sobre autores

P. Boldyrev

National Research Centre Kurchatov Institute

Autor responsável pela correspondência
Email: bol-rev@mail.ru
Rússia, Moscow, 123182

A. Kurochkin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Rússia, Moscow, 123182

R. Nurtdinov

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Rússia, Moscow, 123182

M. Proshin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Rússia, Moscow, 123182

D. Chuvilin

National Research Centre Kurchatov Institute; Department of Chemistry

Email: bol-rev@mail.ru
Rússia, Moscow, 123182; Moscow, 119991

Yu. Yashin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Rússia, Moscow, 123182

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