Electrochemical method for producing radionuclide Lu-177 with high specific activity


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

A modified method for the isolation of radionuclide 177Lu obtained from a Yb-176 target irradiated with thermal neutrons is proposed. The method consists of the combination of two electrochemical processes— cementation of ytterbium acetate–chloride solution to sodium amalgam and subsequent electrolysis of the ytterbium solution in a separate electrolytic cell without adjusting the solution. The electrochemical setup consisting of two cells gives the purification factor of 177Lu from ytterbium at a level of 105–106, which allows using 177Lu of such quality for labeling bioorganic molecules.

About the authors

P. P. Boldyrev

National Research Centre Kurchatov Institute

Author for correspondence.
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182

A. V. Kurochkin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182

R. F. Nurtdinov

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182

M. A. Proshin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182

D. Yu. Chuvilin

National Research Centre Kurchatov Institute; Department of Chemistry

Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182; Moscow, 119991

Yu. A. Yashin

National Research Centre Kurchatov Institute

Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Allerton Press, Inc.