Electrochemical method for producing radionuclide Lu-177 with high specific activity
- Authors: Boldyrev P.P.1, Kurochkin A.V.1, Nurtdinov R.F.1, Proshin M.A.1, Chuvilin D.Y.1,2, Yashin Y.A.1
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Affiliations:
- National Research Centre Kurchatov Institute
- Department of Chemistry
- Issue: Vol 71, No 3 (2016)
- Pages: 193-198
- Section: Article
- URL: https://bakhtiniada.ru/0027-1314/article/view/163255
- DOI: https://doi.org/10.3103/S0027131416030032
- ID: 163255
Cite item
Abstract
A modified method for the isolation of radionuclide 177Lu obtained from a Yb-176 target irradiated with thermal neutrons is proposed. The method consists of the combination of two electrochemical processes— cementation of ytterbium acetate–chloride solution to sodium amalgam and subsequent electrolysis of the ytterbium solution in a separate electrolytic cell without adjusting the solution. The electrochemical setup consisting of two cells gives the purification factor of 177Lu from ytterbium at a level of 105–106, which allows using 177Lu of such quality for labeling bioorganic molecules.
About the authors
P. P. Boldyrev
National Research Centre Kurchatov Institute
Author for correspondence.
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182
A. V. Kurochkin
National Research Centre Kurchatov Institute
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182
R. F. Nurtdinov
National Research Centre Kurchatov Institute
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182
M. A. Proshin
National Research Centre Kurchatov Institute
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182
D. Yu. Chuvilin
National Research Centre Kurchatov Institute; Department of Chemistry
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182; Moscow, 119991
Yu. A. Yashin
National Research Centre Kurchatov Institute
Email: bol-rev@mail.ru
Russian Federation, Moscow, 123182
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