Отправить статью по E-mail T5 Group Bacteriophages as Potential Phage Therapy Agents
- Авторы: Kulikov E.E.1, Golomidova A.K.1, Morozova V.V.2, Kozlova Y.N.2, Letarov A.V.1,3
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Учреждения:
- Winogradsky Institute of Microbiology, Research Center of Biotechnology, Russian Academy of Sciences
- Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
- Moscow State University
- Выпуск: Том 88, № 6 (2019)
- Страницы: 769-772
- Раздел: Short Communications
- URL: https://bakhtiniada.ru/0026-2617/article/view/164173
- DOI: https://doi.org/10.1134/S0026261719060067
- ID: 164173
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Аннотация
The T5 group bacteriophages, which infect a number of enterobacterial species and strains, are useful objects for obtaining therapeutic phage preparations with broad specificity. The present work considers the biological properties of T5-related phages responsible for their ability to infect a broad spectrum of bacterial strains in spite of a limited number of known phage receptor proteins. Ability of bacteriophages to recognize bacterial O-antigens specifically enhances their capacity for infection and increases the therapeutic potential of the T5 phages.
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Об авторах
E. Kulikov
Winogradsky Institute of Microbiology, Research Center of Biotechnology, Russian Academy of Sciences
Email: alla_golomidova@mail.ru
Россия, Moscow, 119071
A. Golomidova
Winogradsky Institute of Microbiology, Research Center of Biotechnology, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: alla_golomidova@mail.ru
Россия, Moscow, 119071
V. Morozova
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: alla_golomidova@mail.ru
Россия, Novosibirsk, 630090
Yu. Kozlova
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: alla_golomidova@mail.ru
Россия, Novosibirsk, 630090
A. Letarov
Winogradsky Institute of Microbiology, Research Center of Biotechnology, Russian Academy of Sciences; Moscow State University
Email: alla_golomidova@mail.ru
Россия, Moscow, 119071; Moscow, 119192
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