Identification of novel gene clusters for secondary metabolism in Trichoderma genomes
- Authors: Bansal R.1, Mukherjee P.K.1
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Affiliations:
- Nuclear Agriculture and Biotechnology Division
- Issue: Vol 85, No 2 (2016)
- Pages: 185-190
- Section: Experimental Articles
- URL: https://bakhtiniada.ru/0026-2617/article/view/162543
- DOI: https://doi.org/10.1134/S002626171602003X
- ID: 162543
Cite item
Abstract
Trichoderma species are widely used in agriculture as biofungicides. These fungi are rich source of secondary metabolites and the mycoparasitic species are enriched in genes for biosynthesis of secondary metabolites. Most often, genes for secondary metabolism are clustered in fungal genomes. Previously, no systematic study was undertaken to identify the secondary-metabolism related gene clusters in Trichoderma genomes. In the present study, a survey of the three Trichoderma genomes viz. T. reesei, T. atroviride and T. virens, was made to identify the putative gene clusters associated with secondary metabolism. In T. reesei genome, we identified one new NRPS and 6 new PKS clusters, which is much less than that found in T. atroviride (4 and 8) and T. virens (8 and 7). This work would pave the way for discovery of novel secondary metabolites and pathways in Trichoderma.
Keywords
About the authors
R. Bansal
Nuclear Agriculture and Biotechnology Division
Email: prasunmukherjee1@gmail.com
India, Trombay, Mumbai, 400085
P. K. Mukherjee
Nuclear Agriculture and Biotechnology Division
Author for correspondence.
Email: prasunmukherjee1@gmail.com
India, Trombay, Mumbai, 400085
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