Мақаланы E-mail арқылы жіберу Structure, DNA bonding, and biological activity of a novel Pb(II) complex of 1,1-bis(5-(pyrazin-2-yl)-1,2,4-triazol-3-yl) methane
- Авторлар: Gao E.1, Meng B.1, Su J.1, Peng T.1, Qi Z.1, Jia B.1, Feng Y.1, Zhu M.1
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Мекемелер:
- Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
- Шығарылым: Том 58, № 8 (2017)
- Беттер: 1560-1566
- Бөлім: Article
- URL: https://bakhtiniada.ru/0022-4766/article/view/161706
- DOI: https://doi.org/10.1134/S0022476617080121
- ID: 161706
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Аннотация
A novel complex [Pb(bptm)(NO3)(H2O)2] (bptm = 1,1-bis(5-(pyrazin-2-yl)-1,2,4-triazol-3-yl) methane) is synthesized and characterized by IR spectroscopy and single crystal X-ray diffraction. Its reactivity with calf thymus DNA and HeLa cell DNA is measured using UV absorption and fluorescence spectroscopies. Gel electrophoresis assay demonstrates the ability of the complex to cleave pBR322 plasmid DNA. Eventually, the complex can suitably dock with a special DNA.
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Авторлар туралы
E.-J. Gao
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
B. Meng
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
J.-Q. Su
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
T.-T. Peng
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
Z.-Z. Qi
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
B. Jia
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
Y.-H. Feng
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
M.-C. Zhu
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Хат алмасуға жауапты Автор.
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang
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