Molecular and Crystal Structure of (1S,2R)-1-{2-[(1S)-1-(Dimethylamino)Ethyl]Phenyl}-1,2-Diphenylethane-1,2-Diol

Abstract

The (R)-configuration of the carbinol center formed as a result of diastereospecific reduction of (2S)-2-{2-(1S)-1-(dimethylamino)ethyl]phenyl}-2-hydroxy-1,2-diphenylethanone is established by the XRD method. The analysis of shortened nonvalent intramolecular contacts testifies that the molecule is quite rigid, despite the presence of a large number of single valence bonds. Layered nature of molecular packaging is revealed.