2-methylpyridinium 5-(2,4-dinitrophenyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-olate: Synthesis, crystal structure, and biological evaluation
- 作者: Mangaiyarkarasi G.1, Sridevi G.1, Poornima Devi P.1, Kalaivani D.1
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隶属关系:
- PG and Research Department of Chemistry
- 期: 卷 57, 编号 5 (2016)
- 页面: 985-990
- 栏目: Article
- URL: https://bakhtiniada.ru/0022-4766/article/view/160253
- DOI: https://doi.org/10.1134/S002247661605019X
- ID: 160253
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详细
The titled complex is synthesized from the ethanolic solutions of 1-chloro-2,4-dinitrobenzene, 2-thiobarbituric acid, and 2-methylpyridine and characterized by spectral and elemental analyses. The single crystal X-ray diffraction results for the complex are compatible with the spectral observations. The titled complex exhibits anticonvulsant activity and reduces all phases of convulsion even at a low dosage. Acute toxicity studies of the complex are performed to understand the safer dose concentration for clinical trials.
作者简介
G. Mangaiyarkarasi
PG and Research Department of Chemistry
Email: kalaivbalaj@yahoo.co.in
印度, Tamil Nadu
G. Sridevi
PG and Research Department of Chemistry
Email: kalaivbalaj@yahoo.co.in
印度, Tamil Nadu
P. Poornima Devi
PG and Research Department of Chemistry
Email: kalaivbalaj@yahoo.co.in
印度, Tamil Nadu
D. Kalaivani
PG and Research Department of Chemistry
编辑信件的主要联系方式.
Email: kalaivbalaj@yahoo.co.in
印度, Tamil Nadu
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