电邮这篇文章 Botulinum toxin type A in the treatment of bladder pain syndrome in women: initial results
- 作者: Al-Shukri S.H.1, Kuzmin I.V.1, Slesarevskaya M.N.1, Ignashov Y.A.1
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隶属关系:
- Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
- 期: 卷 8, 编号 2 (2018)
- 页面: 5-10
- 栏目: Articles
- URL: https://bakhtiniada.ru/uroved/article/view/9111
- DOI: https://doi.org/10.17816/uroved825-10
- ID: 9111
如何引用文章
详细
We present the results of botulinum toxin type A (BT-A) treatment in 49 women (aged 41–65 years) with bladder pain syndrome. Previously, all patients underwent oral and intravesical drug therapy in addition to hydrodistention of the bladder without significant clinical effect. BT-A at a dose of 100 U (20 points at 5 units) was injected into the bladder under general anesthesia. Treatment results were evaluated 3 months after the treatment using specialized questionnaires such as the Pelvic Pain and Urgency/Frequency (PUF) Scale, O’Leary-Sant Symptom Index and Interstitial Cystitis Scale, visual analogue pain scale (VAS), and urinary diaries. Remarkably, the treatment was effective in 46 (93.8%) patients. By the end of the third month after the BT-A injection, the PUF Scale score, the O’Leary-Sant Symptom and Interstitial Cystitis Scale, and VAS reduced by 41.3%, 32%, and 34%, respectively, and urination frequency decreased by 38.5%. Thus, BT-A is an effective method for treating bladder pain syndrome in patients who are refractory to other treatment methods.
作者简介
Salman Al-Shukri
Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
编辑信件的主要联系方式.
Email: alshukri@mail.ru
Doctor of Medical Science, Professor, Head of the Department of Urology
俄罗斯联邦, Saint PetersburgIgor Kuzmin
Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: kuzminigor@mail.ru
Doctor of Medical Science, Professor, Department of Urology
俄罗斯联邦, Saint PetersburgMargarita Slesarevskaya
Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: mns-1971@yandex.ru
Candidate of Medical Science, Senior Research Fellow, Department of Urology
俄罗斯联邦, Saint PetersburgYuriy Ignashov
Academician I.P. Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: yuri.ignashov@gmail.com
Postgraduate, Department of Urology
俄罗斯联邦, Saint Petersburg参考
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