电邮这篇文章 微量营养素缺乏症个性化的矫正作为特发性不育的改善射精质量的治疗策略
- 作者: Tsukanov A.Y.1, Satibaldin D.A.1
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隶属关系:
- Omsk State Medical University of the Ministry of Healthcare of the Russian Federation
- 期: 卷 10, 编号 2 (2020)
- 页面: 143-150
- 栏目: Original articles
- URL: https://bakhtiniada.ru/uroved/article/view/34073
- DOI: https://doi.org/10.17816/uroved102143-150
- ID: 34073
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详细
引言。婚后不育是关键的医学问题之一。几乎50％的情况下，男性不育是婚姻中不育的原因。特发性男性不育症的比例为30-40％。
材料与方法。157例特发性不育患者被随机分为两组。主要组（n = 82）：通过规定最大每日允许剂量的单组分药物，纠正了微量营养素缺乏时的微量营养素水平。对照组（n = 75）（复杂药物的经验疗法）被随机分组到第1组 （对照组1) (n = 38)：与左旋肉碱一起使用的复杂制剂；及第2组（对照组2）（n = 37）：使用不含左旋肉碱的复杂复合维生素制剂。为了确定微量营养素缺乏症，对93名已实现生育功能的健康志愿者进行了检查（当参与研究时，他们的女同伴孕期为最后三个月）。
结果。确定了微量营养素的不足：硒、锌、维生素C、维生素E。使用单组分药物在三个月内进行了校正。在主要组中精子图的所有参数都良好势态。对照组中，射精量、浓度、精子总数数都没有变化，显示出总体和渐进式移动性增加。主要组、对照组1及对照组2中正常精子的比例增加了61.9%、28.6%（与主要组相比 р < 0,01）及20.0%（与主要组相比 р < 0,001）。总体移动性增加了44.5%、24.5%（与主要组相比р < 0.05）到12.0%（与主要组相比 р < 0.001）。
渐进式流动增加了60.4%、54.5%（与主要组相比 р > 0.05）,14.7%（与主要组相比 р < 0.001）。主要组中怀孕率增加了21.9%，对照组1中 — 5.2%（р < 0.05）对照组2 — 2.7%（р < 0.05）。
结论。个性化纠正微量营养素缺乏症为了改善特发性男性不育的射精质量是有效的治疗策略。
作者简介
Anton Tsukanov
Omsk State Medical University of the Ministry of Healthcare of the Russian Federation
编辑信件的主要联系方式.
Email: autt@mail.ru
ORCID iD: 0000-0002-3497-5856
SPIN 代码: 9310-1220
Scopus 作者 ID: 57194497218
Doctor of Medical Science, Professor, Head of the Department of Surgical Diseases and Urology of Postgraduate Education
俄罗斯联邦, OmskDanijar Satibaldin
Omsk State Medical University of the Ministry of Healthcare of the Russian Federation
Email: danijar87@mail.ru
ORCID iD: 0000-0002-3978-1778
Assistant of the Department of Surgical Diseases and Urology of Postgraduate Education
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